Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease.
RatChemical/toxinWistarMaleOral10-20 mg/kg
Model: Intra-colonic TNBS-induced colitis (Crohn's disease model)
Oral ellagic acid reduced colonic injury severity and inflammation in TNBS-induced rat colitis via MAPK and NF-kB pathway modulation.
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