PRECLINICAL PUBLICATION · 2011

Matrix metalloproteinase-9 controls proliferation of NG2+ progenitor cells immediately after spinal cord injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

SB-3CT

PMID 21756907 ↗2011Reported benefit

Matrix metalloproteinase-9 controls proliferation of NG2+ progenitor cells immediately after spinal cord injury.

RatSpinal cord injuryHemisection / partialSprague-DawleyFemaleAcute, for two days after injury

Model: T9-10 spinal cord dorsal hemisection

Acute MMP-9/2 inhibition with SB-3CT increased NG2+ progenitor proliferation, improved remyelination and locomotor and somatosensory recovery after spinal cord injury.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.