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PRECLINICAL PUBLICATION · 2011

Bone marrow-derived mesenchymal stem cells expressing the bFGF transgene promote axon regeneration and functional recovery after spinal cord injury in rats.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21756547 ↗2011Reported benefit

Bone marrow-derived mesenchymal stem cells expressing the bFGF transgene promote axon regeneration and functional recovery after spinal cord injury in rats.

RatSpinal cord injuryUnspecifiedSprague-DawleyMalen = 96Intraspinal injection1x10^6 cellsAfter injury (model established)

Model: Acute spinal cord injury

bFGF gene-modified BMSCs promoted axonal outgrowth and enhanced locomotor recovery after spinal cord injury more than BMSCs alone.

Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.