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PRECLINICAL PUBLICATION · 2011

Vasoactive intestinal peptide promotes gut barrier function against severe acute pancreatitis.

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21725849 ↗2011Reported benefit

Vasoactive intestinal peptide promotes gut barrier function against severe acute pancreatitis.

RatChemical/toxinSprague-Dawleyn = 54Intraperitoneal5 nmolWithin 5 min after model induction

Model: Severe acute pancreatitis (retrograde sodium taurocholate into bili-pancreatic duct)

Vasoactive intestinal peptide reduced endotoxaemia and intestinal inflammation and alleviated gut mucosal injury in severe acute pancreatitis in rats.

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.