Antibodies preventing the interaction of tissue-type plasminogen activator with N-methyl-D-aspartate receptors reduce stroke damages and extend the therapeutic window of thrombolysis.

Antibodies preventing the interaction of tissue-type plasminogen activator with N-methyl-D-aspartate receptors reduce stroke damages and extend the therapeutic window of thrombolysis.

Model: Murine thromboembolic stroke (with or without tPA reperfusion)

Antibodies blocking the tPA-NMDA receptor interaction reduced ischaemic brain damage and extended the therapeutic window of tPA thrombolysis in mice.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.