A novel free radical scavenger rescues retinal cells in vivo.
MouseRadiationBALB/c, C57BL, rd10Intraperitoneal200 mg/kg (light damage model)1 h prior to phototoxicity
Model: Acute light damage (phototoxicity); rd10 inherited retinal degeneration; NMDA excitotoxicity
Systemic BP3, a free radical scavenger, reduced photoreceptor and retinal ganglion cell death and oxidative burden across three mouse models of retinal injury.
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