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PRECLINICAL PUBLICATION · 2011

gamma-glutamylcysteine ethyl ester protects cerebral endothelial cells during injury and decreases blood-brain barrier permeability after experimental brain trauma.

Mouse / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21534958 ↗2011Reported benefit

gamma-glutamylcysteine ethyl ester protects cerebral endothelial cells during injury and decreases blood-brain barrier permeability after experimental brain trauma.

MouseTBIControlled cortical impactC57BL/6Maleintraperitoneal10 min after trauma

Model: controlled cortical impact brain trauma (with in vitro oxidative/OGD)

Post-trauma GCEE reduced acute blood-brain barrier permeability and protected brain endothelial cells against oxidative injury.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.