The antibacterial activity of BF-30 in vitro and in infected burned rats is through interference with cytoplasmic membrane integrity.
RatBurnUnspecifiedSprague-DawleyFemale0.75, 3, 12 mg/kg/dayafter infection
Model: burn wound with Pseudomonas aeruginosa infection
BF-30 dose-dependently reduced P. aeruginosa colonisation in burn eschar and organs and prevented systemic infection.
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.