PRECLINICAL PUBLICATION · 2011

The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21440550 ↗2011Reported benefit

MouseChemical/toxinC57BL/6 (Dkk1d/d doubleridge)during colitis

Model: dextran sulfate sodium (DSS)-induced colitis

Reduced Dkk1 increased epithelial proliferation and accelerated recovery and wound repair after colitis.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.