PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2011

Grafted neural progenitors integrate and restore synaptic connectivity across the injured spinal cord.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21430166 ↗2011Reported benefit

Grafted neural progenitors integrate and restore synaptic connectivity across the injured spinal cord.

RatSpinal cord injuryHemisection / partialSprague-Dawley (alkaline phosphatase transgenic)Femalegrafted into lesion; lentivirus into dorsal column nucleiacutely

Model: dorsal column lesion (C1)

Grafted neural progenitors formed active synaptic relays across the injured spinal cord to the target nuclei.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.