NADPH-d and Fos reactivity in the rat spinal cord following experimental spinal cord injury and embryonic neural stem cell transplantation.
RatSpinal cord injuryHemisection / partialSprague-DawleyMalen = 90 ratsintraperitoneal (drugs); transplantation (cells)L-NAME 75 mg/kg; L-arginine 225 mg/kgacute (2 h) and chronic (28 days)
Model: hemisection spinal cord injury (T12-T13)
Embryonic neural stem cell transplantation improved the acute phase, decreasing Fos and NADPH-d positive neurons around the injury.
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