Protective effects of Mg-CUD against D-galactosamine-induced hepatotoxicity in rats.
RatChemical/toxinSprague-DawleyMaleOral15.625, 31.25 and 62.5 mg/kgOnce daily for 2 weeks and 6 h after D-GalN injection
Model: D-galactosamine-induced acute liver injury (700 mg/kg intraperitoneal)
Mg-CUD ameliorated D-galactosamine-induced acute hepatitis through antioxidative and anti-inflammatory effects and inhibition of NF-kappaB activation.
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