Combination of amlodipine and atorvastatin synergistically reduces leukocyte recruitment to mechanically injured mouse femoral artery.
MouseOtherC57BL/6MaleAmlodipine 0.5 mg/kg/day; atorvastatin 1 mg/kg/dayFor 7 days after injury
Model: Intraluminal wire injury of the femoral artery
Co-administration of low-dose amlodipine and atorvastatin, but not either alone, synergistically inhibited leukocyte recruitment and oxidative stress at the injured artery.
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