Temporal and spatial patterns of endogenous danger signal expression after wound healing and in response to lymphedema.
MouseWoundC57BL/6Female
Model: Surgical mouse tail model of tissue injury and lymphedema
Endogenous danger signals HMGB1 and HSP70 were upregulated along spatial gradients in wound and lymphedema, and HMGB1 blockade reduced inflammatory lymphangiogenesis.
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.