PRECLINICAL PUBLICATION · 2011

Tanshinone IIA ameliorates seawater exposure-induced lung injury by inhibiting aquaporins (AQP) 1 and AQP5 expression in lung.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21244858 ↗2011Reported benefit

RatOtherSprague-Dawley

Model: Seawater aspiration-induced acute lung injury (intratracheal seawater installation)

Tanshinone IIA reduced AQP1 and AQP5 over-expression and alleviated seawater aspiration-induced lung oedema, injury and gas-exchange impairment.

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.