PRECLINICAL PUBLICATION · 2011

Role of reactive oxygen species in injury-induced insulin resistance.

Mouse / Haemorrhage/shock

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21239612 ↗2011Reported benefit

MouseHaemorrhage/shockUnspecifiedC57BL/6 (transgenic)Antioxidant pretreatment before injury

Model: Trauma/injury-induced acute hepatic insulin resistance (critical illness diabetes)

Reducing mitochondrial ROS via SOD2 overexpression or antioxidants prevented acute hepatic insulin resistance and stress signalling after injury.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.