Minocycline neuroprotection in a rat model of asphyxial cardiac arrest is limited.
RatIschaemia-reperfusionCerebral (MCAO/stroke)Pre- or post-arrest (up to 18 h after)
Model: Asphyxial cardiac arrest (5 min) followed by resuscitation
Minocycline transiently reduced neuronal degeneration and microglial response at 7 days (most effective given post-arrest) but the neuroprotection was lost by 21 days.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.