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PRECLINICAL PUBLICATION · 2010

The intriguing effects of ecstasy (MDMA) on cognitive function in mice subjected to a minimal traumatic brain injury (mTBI).

Mouse / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21120456 ↗2010Reported benefit

The intriguing effects of ecstasy (MDMA) on cognitive function in mice subjected to a minimal traumatic brain injury (mTBI).

MouseTBIClosed-head / concussionICRMale10 mg/kg1 h prior to injury

Model: Closed head minimal traumatic brain injury

A single MDMA dose before minimal TBI minimised visual and spatial memory impairment and reversed the injury-induced tyrosine hydroxylase decrease.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.