Inhibition of CXCR1 and CXCR2 chemokine receptors attenuates acute inflammation, preserves gray matter and diminishes autonomic dysreflexia after spinal cord injury.
RatSpinal cord injuryUnspecifiedWistarFemale7.5 or 15 mg/kgAcute after injury
Model: Spinal cord injury at T4
Reparixin reduced acute inflammation, preserved gray matter, mildly improved motor function and reduced autonomic dysreflexia after SCI.
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