PRECLINICAL PUBLICATION · 2011

Cycloxygenase inhibition enhances the effects of surfactant therapy in endotoxin-induced rat model of ARDS.

Rat / Endotoxin/LPS

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 20422273 ↗2011Reported benefit

RatEndotoxin/LPSSprague-DawleyIntratrachealAfter LPS

Model: Intratracheal lipopolysaccharide-induced ARDS

Combining COX inhibition with surfactant reverted LPS-induced reductions in SP-A and reduced PGE2 and COX activity.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.