PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2010

Naturally existing CD11c(low)CD45RB(high) dendritic cells protect mice from acute severe inflammatory response induced by thermal injury.

Mouse / Burn

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 20392518 ↗2010Reported benefit

Naturally existing CD11c(low)CD45RB(high) dendritic cells protect mice from acute severe inflammatory response induced by thermal injury.

MouseBurnScaldBALB/cMaleIntraperitoneal injectionAfter burn

Model: Scald thermal injury (15 percent TBSA)

Adoptive transfer of CD11c-low CD45RB-high dendritic cells reduced inflammatory cytokines and mortality after thermal injury.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.